Stephen Senn Masterclass Dec 2018

A joint CSTAR @ UL/HRI masterclass will be held on December 6-7th on 'Statistical Issues in Clinical Research' taught by Prof Stephen Senn, Edinburgh. This course will run from 9:30-5:30 on day 1, 9-3:00 on day 2 and will be held in the CERC building at UHL. It will include the following topics:

  • Philosophy (Causality and thinking statistically)
  • Theory (An elementary explanation of the differences between Bayesians and  frequentists)
  • Practical (Design, allocation to treatment and sample size determination)
  • Baseline and Covariate Information (if, when and how to adjust Measuring Treatment Effects (Transformations, dichotomies, intention to treat, missing data and multiplicity)
  • Beyond the Single Centre Parallel Group Trial (Multi-centre trials, cross-over trials and cluster randomised trials)
  • Beyond average effects? (Subgroups, personalised medicine, n-of .1 trials and real world data)


Although mainly aimed at those involved in health research, it could also be useful for those making similar decisions/interpretations in their analyses. A basic statistical knowledge is all that is required.

Prof Stephen Senn has had a wide range of experiences in academia, the pharmaceutical industry and the National Health Service in England. From 2011 to 2018, he was at the Luxembourg Institute of Health and was previously a Professor in Statistics at the University of Glasgow (2003) and University College London (1995-2003). He is the author of three influential books, Cross-over Trials in Clinical Research (1993 & 2002), Statistical Issues in Drug Development (1997, 2007) and Dicing with Death (2003).  His expertise is in statistical methods for drug development and statistical inference. He is well known as a lively and stimulating speaker on the statistical aspects of clinical trials.

Please enrol by emailing for a registration form. Fees for those outside UL are €250 for the 2 day course.There will be a limit on numbers overall, so please enrol early if you can. A list of further masterclasses for next year (2019) will be announced in due course on the CSTAR website. Details of other courses running this year by CSTAR@UL can be found here.